| Event | Date | Location | |
| Clemson Tigers vs Presbyterian Blue Hose | Fri. Nov 13, 2009 8:00PM | Clemson, SC - Littlejohn Coliseum |  |
| Clemson Tigers vs Winthrop Eagles | Mon. Nov 23, 2009 7:30PM | Clemson, SC - Littlejohn Coliseum | |
| WBCA Classic: UConn Huskies vs Clemson Tigers (WOMEN) | Sun. Nov 29, 2009 4:30PM | Storrs Mansfield, CT - Gampel Pavilion | |
| Clemson Tigers vs Illinois Fighting Illini | Wed. Dec 2, 2009 7:15PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs South Carolina Gamecocks | Sun. Dec 6, 2009 1:00PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs Furman Paladins | Sun. Dec 13, 2009 4:00PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs Charleston Cougars | Sat. Dec 19, 2009 TBA | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs Western Carolina Catamounts | Tue. Dec 22, 2009 7:30PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs South Carolina State Bulldogs | Tue. Dec 29, 2009 7:30PM | Clemson, SC - Littlejohn Coliseum | |
| Duke Blue Devils vs Clemson Tigers | Sun. Jan 3, 2010 7:45PM | Durham, NC - Cameron Indoor Stadium | |
| Clemson Tigers vs Boston College Eagles | Sat. Jan 9, 2010 4:00PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs North Carolina Tar Heels | Wed. Jan 13, 2010 9:00PM | Clemson, SC - Littlejohn Coliseum | |
| North Carolina State Wolfpack vs Clemson Tigers | Sat. Jan 16, 2010 12:00PM | Raleigh, NC - Rbc Center | |
| Georgia Tech Yellow Jackets vs Clemson Tigers | Tue. Jan 19, 2010 7:00PM | Atlanta, GA - Alexander Memorial Coliseum | |
| Clemson Tigers vs Duke Blue Devils | Sat. Jan 23, 2010 9:00PM | Clemson, SC - Littlejohn Coliseum | |
| Boston College Eagles vs Clemson Tigers | Tue. Jan 26, 2010 7:00PM | Chestnut Hill, MA - Conte Forum | |
| Clemson Tigers vs Maryland Terrapins | Sun. Jan 31, 2010 5:30PM | Clemson, SC - Littlejohn Coliseum | |
| Virginia Tech Hokies vs Clemson Tigers | Sat. Feb 6, 2010 4:00PM | Blacksburg, VA - Cassell Coliseum | |
| Clemson Tigers vs Florida State Seminoles | Wed. Feb 10, 2010 7:00PM | Clemson, SC - Littlejohn Coliseum | |
| Clemson Tigers vs Miami Hurricanes | Sat. Feb 13, 2010 12:00PM | Clemson, SC - Littlejohn Coliseum | |
| Maryland Terrapins vs Clemson Tigers (WOMEN) | Sun. Feb 14, 2010 2:00PM | College Park, MD - Comcast Center - MD | |
| Clemson Tigers vs Virginia Cavaliers | Sat. Feb 20, 2010 4:00PM | Clemson, SC - Littlejohn Coliseum | |
| Maryland Terrapins vs Clemson Tigers | Wed. Feb 24, 2010 9:00PM | College Park, MD - Comcast Center - MD | |
| Clemson Tigers vs Georgia Tech Yellow Jackets | Tue. Mar 2, 2010 8:00PM | Clemson, SC - Littlejohn Coliseum | |
| Wake Forest Demon Deacons vs Clemson Tigers | Sun. Mar 7, 2010 6:00PM | Winston Salem, NC - Winston-salem Entertainment Sports Complex (formerly Lawrence Joel Veterans Memorial Coliseum) | |
