| Event | Date | Location | |
| Kansas City Royals vs Detroit Tigers | Mon. Apr 5, 2010 TBA | Kansas City, MO - Kauffman Stadium |  |
| Kansas City Royals vs Detroit Tigers | Wed. Apr 7, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Kansas City Royals vs Detroit Tigers | Thu. Apr 8, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Detroit Tigers vs Cleveland Indians | Fri. Apr 9, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Cleveland Indians | Sat. Apr 10, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Cleveland Indians | Sun. Apr 11, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Kansas City Royals | Mon. Apr 12, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Kansas City Royals | Tue. Apr 13, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Kansas City Royals | Wed. Apr 14, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Seattle Mariners vs Detroit Tigers | Fri. Apr 16, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sat. Apr 17, 2010 6:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sun. Apr 18, 2010 1:10PM | Seattle, WA - Safeco Field | |
| Los Angeles Angels of Anaheim vs Detroit Tigers | Mon. Apr 19, 2010 TBA | Anaheim, CA - Angel Stadium | |
| Los Angeles Angels of Anaheim vs Detroit Tigers | Tue. Apr 20, 2010 TBA | Anaheim, CA - Angel Stadium | |
| Los Angeles Angels of Anaheim vs Detroit Tigers | Wed. Apr 21, 2010 TBA | Anaheim, CA - Angel Stadium | |
| Los Angeles Angels of Anaheim vs Detroit Tigers | Thu. Apr 22, 2010 TBA | Anaheim, CA - Angel Stadium | |
| Texas Rangers vs Detroit Tigers | Fri. Apr 23, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Detroit Tigers | Sat. Apr 24, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Detroit Tigers | Sun. Apr 25, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Detroit Tigers | Mon. Apr 26, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Detroit Tigers vs Minnesota Twins | Tue. Apr 27, 2010 7:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Minnesota Twins | Wed. Apr 28, 2010 7:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Minnesota Twins | Thu. Apr 29, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Los Angeles Angels of Anaheim | Fri. Apr 30, 2010 7:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Los Angeles Angels of Anaheim | Sat. May 1, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Detroit Tigers vs Los Angeles Angels of Anaheim | Sun. May 2, 2010 1:05PM | Detroit, MI - Comerica Park | |
| Minnesota Twins vs Detroit Tigers | Mon. May 3, 2010 7:10PM | Minneapolis, MN - Target Field | |
| Minnesota Twins vs Detroit Tigers | Tue. May 4, 2010 7:10PM | Minneapolis, MN - Target Field | |
| Minnesota Twins vs Detroit Tigers | Wed. May 5, 2010 12:10PM | Minneapolis, MN - Target Field | |
| Cleveland Indians vs Detroit Tigers | Fri. May 7, 2010 TBA | Cleveland, OH - Progressive Field (formerly Jacobs Field) | |
