| Event | Date | Location | |
| Duke Blue Devils vs North Carolina Greensboro Spartans | Fri. Nov 13, 2009 7:00PM | Durham, NC - Cameron Indoor Stadium |  |
| Duke Blue Devils vs Coastal Carolina Chanticleers | Mon. Nov 16, 2009 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Elon Phoenix | Tue. Nov 17, 2009 6:00PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Radford Highlanders | Sat. Nov 21, 2009 2:00PM | Durham, NC - Cameron Indoor Stadium | |
| Wisconsin Badgers vs Duke Blue Devils | Wed. Dec 2, 2009 8:15PM | Madison, WI - Kohl Center | |
| Duke Blue Devils vs St. Johns Red Storm | Sat. Dec 5, 2009 3:30PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Gardner-Webb Runnin Bulldogs | Tue. Dec 15, 2009 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Aeropostale Classic: Gonzaga Bulldogs vs Duke Blue Devils | Sat. Dec 19, 2009 4:00PM | New York, NY - Madison Square Garden | |
| Duke Blue Devils vs Long Beach State Forty Niners | Tue. Dec 29, 2009 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Pennsylvania Quakers | Thu. Dec 31, 2009 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Clemson Tigers | Sun. Jan 3, 2010 7:45PM | Durham, NC - Cameron Indoor Stadium | |
| Iowa State Cyclones vs Duke Blue Devils | Wed. Jan 6, 2010 9:00PM | Chicago, IL - United Center | |
| Georgia Tech Yellow Jackets vs Duke Blue Devils | Sat. Jan 9, 2010 2:00PM | Atlanta, GA - Alexander Memorial Coliseum | |
| Duke Blue Devils vs Boston College Eagles | Wed. Jan 13, 2010 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Wake Forest Demon Deacons | Sun. Jan 17, 2010 8:00PM | Durham, NC - Cameron Indoor Stadium | |
| North Carolina State Wolfpack vs Duke Blue Devils | Wed. Jan 20, 2010 9:00PM | Raleigh, NC - Rbc Center | |
| Clemson Tigers vs Duke Blue Devils | Sat. Jan 23, 2010 9:00PM | Clemson, SC - Littlejohn Coliseum | |
| Maryland Terrapins vs Duke Blue Devils (WOMEN) | Sun. Jan 24, 2010 8:00PM | College Park, MD - Comcast Center - MD | |
| Duke Blue Devils vs Florida State Seminoles | Wed. Jan 27, 2010 9:00PM | Durham, NC - Cameron Indoor Stadium | |
| Georgetown Hoyas vs Duke Blue Devils | Sat. Jan 30, 2010 1:00PM | Washington, DC - Verizon Center - DC | |
| Duke Blue Devils vs Georgia Tech Yellow Jackets | Thu. Feb 4, 2010 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Boston College Eagles vs Duke Blue Devils | Sat. Feb 6, 2010 2:00PM | Chestnut Hill, MA - Conte Forum | |
| Duke Blue Devils vs North Carolina Tar Heels (WOMEN) | Mon. Feb 8, 2010 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| North Carolina Tar Heels vs Duke Blue Devils | Wed. Feb 10, 2010 9:00PM | Chapel Hill, NC - Dean E Smith Center | |
| Duke Blue Devils vs Maryland Terrapins | Sat. Feb 13, 2010 1:00PM | Durham, NC - Cameron Indoor Stadium | |
| Miami Hurricanes vs Duke Blue Devils | Wed. Feb 17, 2010 7:00PM | Miami, FL - Bankunited Center At Um | |
| Duke Blue Devils vs Virginia Tech Hokies | Sun. Feb 21, 2010 6:30PM | Durham, NC - Cameron Indoor Stadium | |
| Duke Blue Devils vs Tulsa Golden Hurricane | Thu. Feb 25, 2010 7:00PM | Durham, NC - Cameron Indoor Stadium | |
| Virginia Cavaliers vs Duke Blue Devils | Sun. Feb 28, 2010 7:45PM | Charlottesville, VA - John Paul Jones Arena | |
| Maryland Terrapins vs Duke Blue Devils | Wed. Mar 3, 2010 9:00PM | College Park, MD - Comcast Center - MD | |
