| Event | Date | Location | |
| Iowa State Cyclones vs Idaho State Bengals | Fri. Nov 13, 2009 7:00PM | Ames, IA - Hilton Coliseum |  |
| Iowa State Cyclones vs Chicago State Cougars | Sun. Nov 15, 2009 6:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Mississippi Valley Delta Devils | Sun. Nov 22, 2009 1:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Tennessee State Tigers | Tue. Nov 24, 2009 7:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Northern Iowa Panthers | Wed. Dec 2, 2009 7:00PM | Ames, IA - Hilton Coliseum | |
| California Golden Bears vs Iowa State Cyclones | Sat. Dec 5, 2009 8:00PM | Berkeley, CA - Haas Pavilion | |
| Iowa State Cyclones vs Iowa Hawkeyes | Fri. Dec 11, 2009 7:00PM | Ames, IA - Hilton Coliseum | |
| Minnesota Golden Gophers vs Iowa State Cyclones (WOMEN) | Sun. Dec 13, 2009 3:30PM | Minneapolis, MN - Williams Arena | |
| Iowa State Cyclones vs Bradley Braves | Sun. Dec 20, 2009 1:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs North Dakota Fighting Sioux | Tue. Dec 22, 2009 7:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Houston Jaguars | Sun. Jan 3, 2010 1:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Duke Blue Devils | Wed. Jan 6, 2010 9:00PM | Chicago, IL - United Center | |
| Iowa State Cyclones vs North Dakota State Bisons | Sat. Jan 9, 2010 3:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Texas Longhorns | Wed. Jan 13, 2010 7:00PM | Ames, IA - Hilton Coliseum | |
| Nebraska Cornhuskers vs Iowa State Cyclones | Sat. Jan 16, 2010 7:00PM | Lincoln, NE - Bob Devaney Center | |
| Texas Tech Red Raiders vs Iowa State Cyclones | Wed. Jan 20, 2010 6:30PM | Lubbock, TX - United Spirit Arena | |
| Iowa State Cyclones vs Kansas Jayhawks | Sat. Jan 23, 2010 1:00PM | Ames, IA - Hilton Coliseum | |
| Oklahoma Sooners vs Iowa State Cyclones | Wed. Jan 27, 2010 8:00PM | Norman, OK - Lloyd Noble Center | |
| Iowa State Cyclones vs Colorado Buffaloes | Sat. Jan 30, 2010 8:00PM | Ames, IA - Hilton Coliseum | |
| Baylor Bears vs Iowa State Cyclones | Wed. Feb 3, 2010 6:30PM | Waco, TX - Ferrell Center | |
| Iowa State Cyclones vs Kansas State Wildcats | Sat. Feb 6, 2010 1:00PM | Ames, IA - Hilton Coliseum | |
| Missouri Tigers vs Iowa State Cyclones | Wed. Feb 10, 2010 6:30PM | Columbia, MO - Mizzou Sports Arena | |
| Kansas Jayhawks vs Iowa State Cyclones | Sat. Feb 13, 2010 7:00PM | Lawrence, KS - Allen Fieldhouse | |
| Iowa State Cyclones vs Oklahoma State Cowboys | Wed. Feb 17, 2010 7:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Texas A&M Aggies | Sat. Feb 20, 2010 3:00PM | Ames, IA - Hilton Coliseum | |
| Iowa State Cyclones vs Nebraska Cornhuskers | Wed. Feb 24, 2010 6:30PM | Ames, IA - Hilton Coliseum | |
| Colorado Buffaloes vs Iowa State Cyclones | Sat. Feb 27, 2010 11:30AM | Boulder, CO - Coors Event Center | |
| Iowa State Cyclones vs Missouri Tigers | Tue. Mar 2, 2010 7:00PM | Ames, IA - Hilton Coliseum | |
