| Event | Date | Location | |
| Oakland Athletics vs Seattle Mariners | Mon. Apr 5, 2010 TBA | Oakland, CA - Oakland-Alameda County Coliseum |  |
| Texas Rangers vs Seattle Mariners | Fri. Apr 9, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Seattle Mariners | Sat. Apr 10, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Seattle Mariners | Sun. Apr 11, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Seattle Mariners vs Oakland Athletics | Mon. Apr 12, 2010 TBA | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Oakland Athletics | Tue. Apr 13, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Oakland Athletics | Wed. Apr 14, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Fri. Apr 16, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sat. Apr 17, 2010 6:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sun. Apr 18, 2010 1:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Mon. Apr 19, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Tue. Apr 20, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Wed. Apr 21, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Chicago White Sox vs Seattle Mariners | Fri. Apr 23, 2010 TBA | Chicago, IL - US Cellular Field | |
| Chicago White Sox vs Seattle Mariners | Sat. Apr 24, 2010 TBA | Chicago, IL - US Cellular Field | |
| Chicago White Sox vs Seattle Mariners | Sun. Apr 25, 2010 TBA | Chicago, IL - US Cellular Field | |
| Kansas City Royals vs Seattle Mariners | Mon. Apr 26, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Kansas City Royals vs Seattle Mariners | Tue. Apr 27, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Kansas City Royals vs Seattle Mariners | Wed. Apr 28, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Seattle Mariners vs Texas Rangers | Fri. Apr 30, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Texas Rangers | Sat. May 1, 2010 6:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Texas Rangers | Sun. May 2, 2010 1:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Tampa Bay Rays | Tue. May 4, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Tampa Bay Rays | Wed. May 5, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Tampa Bay Rays | Thu. May 6, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Los Angeles Angels of Anaheim | Fri. May 7, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Los Angeles Angels of Anaheim | Sat. May 8, 2010 6:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Los Angeles Angels of Anaheim | Sun. May 9, 2010 1:10PM | Seattle, WA - Safeco Field | |
| Baltimore Orioles vs Seattle Mariners | Tue. May 11, 2010 TBA | Baltimore, MD - Oriole Park At Camden Yards | |
| Baltimore Orioles vs Seattle Mariners | Wed. May 12, 2010 TBA | Baltimore, MD - Oriole Park At Camden Yards | |
