| Event | Date | Location | |
| Spring Training: Chicago White Sox vs Seattle Mariners | Mon. Mar 8, 2010 TBA | Phoenix, AZ - Camelback Ranch Stadium |  |
| Spring Training: San Francisco Giants vs Seattle Mariners | Thu. Mar 11, 2010 1:05PM | Scottsdale, AZ - Scottsdale Stadium | |
| Spring Training: Cincinnati Reds vs Seattle Mariners | Fri. Mar 19, 2010 1:05PM | Goodyear, AZ - Goodyear Ballpark | |
| Spring Training: Cleveland Indians vs Seattle Mariners | Thu. Mar 25, 2010 1:05PM | Goodyear, AZ - Goodyear Ballpark | |
| Spring Training: Los Angeles Dodgers vs Seattle Mariners | Sat. Mar 27, 2010 1:05PM | Phoenix, AZ - Camelback Ranch Stadium | |
| Spring Training: Oakland Athletics vs Seattle Mariners | Mon. Mar 29, 2010 1:05PM | Phoenix, AZ - Phoenix Municipal Stadium | |
| Oakland Athletics vs Seattle Mariners | Mon. Apr 5, 2010 7:05PM | Oakland, CA - Oakland-Alameda County Coliseum | |
| Oakland Athletics vs Seattle Mariners | Tue. Apr 6, 2010 7:05PM | Oakland, CA - Oakland-Alameda County Coliseum | |
| Oakland Athletics vs Seattle Mariners | Wed. Apr 7, 2010 7:05PM | Oakland, CA - Oakland-Alameda County Coliseum | |
| Oakland Athletics vs Seattle Mariners | Thu. Apr 8, 2010 12:35PM | Oakland, CA - Oakland-Alameda County Coliseum | |
| Texas Rangers vs Seattle Mariners | Fri. Apr 9, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Seattle Mariners | Sat. Apr 10, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Texas Rangers vs Seattle Mariners | Sun. Apr 11, 2010 TBA | Arlington, TX - Rangers Ballpark In Arlington | |
| Seattle Mariners vs Oakland Athletics | Mon. Apr 12, 2010 TBA | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Oakland Athletics | Tue. Apr 13, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Oakland Athletics | Wed. Apr 14, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Fri. Apr 16, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sat. Apr 17, 2010 6:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Detroit Tigers | Sun. Apr 18, 2010 1:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Mon. Apr 19, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Tue. Apr 20, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Baltimore Orioles | Wed. Apr 21, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Chicago White Sox vs Seattle Mariners | Fri. Apr 23, 2010 TBA | Chicago, IL - US Cellular Field | |
| Chicago White Sox vs Seattle Mariners | Sat. Apr 24, 2010 TBA | Chicago, IL - US Cellular Field | |
| Chicago White Sox vs Seattle Mariners | Sun. Apr 25, 2010 TBA | Chicago, IL - US Cellular Field | |
| Kansas City Royals vs Seattle Mariners | Mon. Apr 26, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Kansas City Royals vs Seattle Mariners | Tue. Apr 27, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Kansas City Royals vs Seattle Mariners | Wed. Apr 28, 2010 TBA | Kansas City, MO - Kauffman Stadium | |
| Seattle Mariners vs Texas Rangers | Fri. Apr 30, 2010 7:10PM | Seattle, WA - Safeco Field | |
| Seattle Mariners vs Texas Rangers | Sat. May 1, 2010 6:10PM | Seattle, WA - Safeco Field | |
