| Event | Date | Location | |
| Preseason: Kansas City Chiefs vs St. Louis Rams | Thu. Aug 28, 2008 7:00PM | Kansas City, MO - Arrowhead Stadium |  |
| Philadelphia Eagles vs St. Louis Rams | Sun. Sep 7, 2008 1:00PM | Philadelphia, PA - Lincoln Financial Field | |
| St. Louis Rams vs New York Giants | Sun. Sep 14, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| Seattle Seahawks vs St. Louis Rams | Sun. Sep 21, 2008 1:05PM | Seattle, WA - Qwest Field | |
| St. Louis Rams vs Buffalo Bills | Sun. Sep 28, 2008 3:05PM | Saint Louis, MO - Edward Jones Dome | |
| Washington Redskins vs St. Louis Rams | Sun. Oct 12, 2008 1:00PM | Hyattsville, MD - Fedex Field | |
| St. Louis Rams vs Dallas Cowboys | Sun. Oct 19, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| New England Patriots vs St. Louis Rams | Sun. Oct 26, 2008 1:00PM | Foxboro, MA - Gillette Stadium | |
| St. Louis Rams vs Arizona Cardinals | Sun. Nov 2, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| New York Jets vs St. Louis Rams | Sun. Nov 9, 2008 1:00PM | East Rutherford, NJ - Giants Stadium | |
| San Francisco 49ers vs St. Louis Rams | Sun. Nov 16, 2008 1:05PM | San Francisco, CA - Candlestick Park | |
| St. Louis Rams vs Chicago Bears | Sun. Nov 23, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| St. Louis Rams vs Miami Dolphins | Sun. Nov 30, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| Arizona Cardinals vs St. Louis Rams | Sun. Dec 7, 2008 2:15PM | Glendale, AZ - University Of Phoenix Stadium | |
| St. Louis Rams vs Seattle Seahawks | Sun. Dec 14, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| St. Louis Rams vs San Francisco 49ers | Sun. Dec 21, 2008 12:00PM | Saint Louis, MO - Edward Jones Dome | |
| Atlanta Falcons vs St. Louis Rams | Sun. Dec 28, 2008 1:00PM | Atlanta, GA - Georgia Dome | |
