| Event | Date | Location | |
| Virginia Tech Hokies vs Brown Bears | Sun. Nov 15, 2009 4:00PM | Blacksburg, VA - Cassell Coliseum |  |
| Virginia Tech Hokies vs North Carolina Greensboro Spartans | Tue. Nov 17, 2009 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Iowa Hawkeyes vs Virginia Tech Hokies | Tue. Dec 1, 2009 8:30PM | Iowa City, IA - Carver Hawkeye Arena | |
| Virginia Tech Hokies vs Georgia Bulldogs | Sun. Dec 6, 2009 3:30PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs Virginia Military Keydets | Wed. Dec 9, 2009 7:30PM | Blacksburg, VA - Cassell Coliseum | |
| Penn State Nittany Lions vs Virginia Tech Hokies | Sat. Dec 12, 2009 8:00PM | University Park, PA - Bryce Jordan Center | |
| Virginia Tech Hokies vs Charleston Southern Buccaneers | Sat. Dec 19, 2009 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs UMBC Retrievers | Tue. Dec 22, 2009 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs Longwood Lancers | Wed. Dec 30, 2009 2:00PM | Blacksburg, VA - Cassell Coliseum | |
| North Carolina Tar Heels vs Virginia Tech Hokies | Sun. Jan 10, 2010 7:45PM | Chapel Hill, NC - Dean E Smith Center | |
| Virginia Tech Hokies vs Miami Hurricanes | Wed. Jan 13, 2010 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs North Carolina Central Eagles | Mon. Jan 18, 2010 8:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs Boston College Eagles | Sat. Jan 23, 2010 1:30PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Cavaliers vs Virginia Tech Hokies | Thu. Jan 28, 2010 TBA | Charlottesville, VA - John Paul Jones Arena | |
| Miami Hurricanes vs Virginia Tech Hokies | Sun. Jan 31, 2010 1:00PM | Miami, FL - Bankunited Center At Um | |
| Virginia Tech Hokies vs North Carolina Tar Heels | Thu. Feb 4, 2010 9:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs Clemson Tigers | Sat. Feb 6, 2010 4:00PM | Blacksburg, VA - Cassell Coliseum | |
| North Carolina State Wolfpack vs Virginia Tech Hokies | Wed. Feb 10, 2010 9:00PM | Raleigh, NC - Rbc Center | |
| Virginia Tech Hokies vs Virginia Cavaliers | Sat. Feb 13, 2010 8:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs Wake Forest Demon Deacons | Tue. Feb 16, 2010 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Duke Blue Devils vs Virginia Tech Hokies | Sun. Feb 21, 2010 6:30PM | Durham, NC - Cameron Indoor Stadium | |
| Boston College Eagles vs Virginia Tech Hokies | Wed. Feb 24, 2010 7:00PM | Chestnut Hill, MA - Conte Forum | |
| Virginia Tech Hokies vs Maryland Terrapins | Sat. Feb 27, 2010 4:00PM | Blacksburg, VA - Cassell Coliseum | |
| Virginia Tech Hokies vs North Carolina State Wolfpack | Wed. Mar 3, 2010 7:00PM | Blacksburg, VA - Cassell Coliseum | |
| Georgia Tech Yellow Jackets vs Virginia Tech Hokies | Sat. Mar 6, 2010 4:00PM | Atlanta, GA - Alexander Memorial Coliseum | |
